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Upstream product

• 99058-02-3 1,1-dibromo-2-(phenylmethyl)cyclopropane 
• 300-57-2 allylbenzene 
• 75-25-2 Bromoform 

Relevant academic research and scientific papers

Chromium-catalyzed cyclopropanation of alkenes with bromoform in the presence of 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-dihydropyrazine

Chromium-catalyzed cyclopropanation of alkenes with bromoform was achieved to produce the corresponding bromocyclopropanes. In this catalytic cyclopropanation, an organosilicon reductant, 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-dihydropyrazine (1a

Can relief of ring-strain in a cyclopropylmethyllithium drive the Brook rearrangement?

α-Cyclopropyl-α-trialkylsilyl alkoxides were formed either by addition of cyclopropyllithiums to acylsilanes or by addition of organolithiums to a cyclopropylformylsilane. [1,2]-Brook rearrangement led to α-silyloxy organolithiums which on warming underwent cyclopropane ring opening and [1,5]-retro-Brook rearrangement to yield γ-silyl ketones. Despite the favourability of the cyclopropane ring opening, the Brook rearrangement still required the presence of an anion stabilising group to proceed. β-Silylketones were similarly formed by Brook-retro-Brook rearrangement on warming acylsilanes with a vinyllithium.

EFFICIENT METHOD FOR THE SYNTHESIS OF MONOHALOCYCLOPROPANES BY REDUCTION OF GEM-DIHALOCYCLOPROPANES BY REDUCTION OF GEM-DIHALOCYCLOPROPANES WITH i-Bu2AlH IN THE PRESENCE OF Ti AND Zr COMPLEXES

We have investigated the reductive dehalogenation reaction of alkyl and aryl substituted gem-dihalocyclopropanes with diisobutyl aluminum hydride in the presence of catalytic amounts of titanium and zirconium complexes.As a result we propose a general method for the synthesis of substituted monohalocyclopropanes and cyclopropanes of various structures.We have also studied the stereochemistry of the reduction.