128997-35-3

Upstream product

• 128997-72-8 1-(4-chlorophenyl)-5-(4-(methylsulfonyl)phenyl)-3-(methylthio)-1H-1,2,4-triazole 
• 1254037-53-0 C₁₅H₁₄ClN₃O₃S₂ 
• 1254037-61-0 C₁₅H₁₂ClN₃O₂S₂ 
• 40913-92-6 4-methylsulfonylbenzoyl chloride 
• 7382-41-4 p-chlorophenyl thiosemicarbazide 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of 1,5-diaryl-1,2,4-triazole derivatives as selective cyclooxygenase-2 inhibitors

A series of 1,5-diaryl-1,2,4-triazole derivatives were synthesized and evaluated as cyclooxygenase-2 (COX-2) inhibitors. The results of the preliminary biological assays in vivo showed that eight compounds 5b, 6b, 6c, 7c, 8b, 8d, 9c, and 9d have potent an

Preparation and antiarthritic activity of new 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones

A series of 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones was synthesized and evaluated as antiinflammatory agents in the rat adjuvant induced arthritis assay.Several analogues were found to be more potent than phenyl