1290050-27-9

Basic information

• Product Name: 4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid (3-chloro-phenyl)-amide
• Synonyms: 4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid (3-chloro-phenyl)-amide
• CAS NO: 1290050-27-9
• Molecular Weight: 462.977
• Mol File: 1290050-27-9.mol

Chemical Properties

• CAS DataBase Reference: 4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid (3-chloro-phenyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid (3-chloro-phenyl)-amide(1290050-27-9)
• EPA Substance Registry System: 4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid (3-chloro-phenyl)-amide(1290050-27-9)

Safety Data

• Hazardous Substances Data: 1290050-27-9(Hazardous Substances Data)

Upstream product

• 1103501-90-1 (S)-6-aza-spiro[2.5]octan-4-ol 
• 1290048-27-9 4-(4-hydroxy-butyl)-5-oxo-[1,4]diazepane-1-carboxylic acid benzyl ester 
• 1290048-29-1 4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid benzyl ester 
• 1290048-25-7 4-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-5-oxo-[1,4]diazepane-1-carboxylic acid benzyl ester 
• 1101840-81-6 (S)-6-Benzyl-6-aza-spiro[2.5]octan-4-ol 
• 1101840-77-0 6-benzyl-6-aza-spiro[2.5]octan-4-one hydrochloride 
• 1101840-76-9 1-[2-(benzyl-tert-butoxycarbonylmethyl-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester 
• 108546-98-1 1-allyl-cyclopropanecarboxylic acid tert-butyl ester 
• 452911-09-0 tert-butyl 1-(2-oxoethyl)cyclopropane-1-carboxylate 
• 1101840-74-7 4-Oxo-6-aza-spiro[2,5]octane-6-carboxylic acid tert-butyl ester 
• 1101840-73-6 (S)-4-hydroxy-6-aza-spiro[2.5]octane-6-carboxylic acid tert-butyl ester 
• 1101840-72-5 tert-butyl 4-hydroxy-6-azaspiro[2.5]octane-6-carboxylate 
• 1103501-89-8 (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride 
• 784156-97-4 benzyl 6-amino-5-oxo-1,4-diazepane-1-carboxylate 

Relevant articles and documents

DIAZEPAM DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS

The invention is concerned with novel bicyclic compounds of Formula (I), wherein n, m, p, A, L, R1, R2, R3, R4, R5, R6, R7, R7, R8, R9 and R10 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor and can be used as medicaments.

NOVEL HETEROCYCLYL COMPOUNDS

The invention is concerned with novel bicyclic compounds of formula (I), wherein n, m, p, A, L, R1, R2, R3, R4, R5, R6, R7, R7, R8, R9, and R10 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor may be used, for example, in the prevention and/or treatment of inflammatory diseases, particularly peripheral arterial occlusive diseases or atherothrombosis.