1290128-07-2

Upstream product

• 685886-67-3 [2,6-dimethoxy-4-(methoxymethyl)phenyl]boronic acid 
• 1290127-77-3 tert-butyl [3-bromo-6-methyl-2-(methylthio)pyrazolo[5,1-b][1,3]thiazol-7-yl]carbamate 
• 1290127-74-0 ethyl 7-[(tert-butoxycarbonyl)amino]-6-methyl-2-(methylthio)pyrazolo[5,1-b][1,3]thiazole-3-carboxylate 
• 1290127-76-2 7-[(tert-butoxycarbonyl)amino]-6-methyl-2-(methylthio)pyrazolo[5,1-b][1,3]thiazole-3-carboxylic acid 

Downstream Products

• 1290128-08-3 C₂₆H₃₅N₃O₅S₂ 
• 1290126-62-3 N-(Cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methyl-2-(methylthio)-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[5,1-b][1,3]thiazole-7-amine 

Relevant academic research and scientific papers

PYRAZOLOTHIAZOLE COMPOUND

A compound represented by the formula (I) or pharmacologically acceptable salt thereof exhibits an excellent CRF receptor antagonism wherein X is a nitrogen atom or CH; R1 is -A11-A12; A11 is a single bond or a C1-6 alkylene group; A12 is a hydrogen atom, a C1-6 alkyl group or a C3-6 cycloalkyl group, etc.; R2 is -A21-A22; A21 is a single bond or a C1-6 alkylene group; A22 is a hydrogen atom, a C1-6 alkyl group, a C3-6 cycloalkyl group, a non-aromatic heterocyclic group, or a heteroaryl group, etc.; R3 is a C 1-6 alkyl group, a C3-6 cycloalkyl group, a C1-6 alkoxy group, a C3-6 cycloalkoxy C1-6 alkyl group, di-C1-6 alkyl amino group, a halogen atom, a cyano group, a formyl group, or a carboxyl group, etc; R4 is a hydrogen atom or a C1-6 alkoxy group; R5 is a halogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group; R6 is a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, a C1-6 alkylthio group, or a C1-6 alkyl sulfinyl group etc.; and R7 is a C1-6 alkyl group, a C1-6 alkoxy group, or a C1-6 alkylthio group