129046-87-3

Basic information

• Product Name: BOC-ASP-OFM
• Synonyms: n-alpha-tert-butyloxycarbonylasparticacidbeta-fluorenylmethylester;BOC-ASP-OFM;BOC-ASPARTIC ACID-OFM;BOC-L-ASPARTIC ACID ALPHA-9-FLUORENYLMETHYL ESTER;N-ALPHA-T-BUTOXYCARBONYL-L-ASPARTIC ACID ALPHA-9-FLUORENYLMETHYL ESTER;N-(tert-Butoxycarbonyl)-L-aspartic acid 1-(9H-fluorene-9-ylmethyl) ester;N-(tert-Butyloxycarbonyl)-L-aspartic acid 1-(9H-fluorene-9-ylmethyl) ester;N-Boc-L-Aspartic acid 1-(9H-fluoren-9-ylmethyl) ester
• CAS NO: 129046-87-3
• Molecular Formula: C₂₃H₂₅NO₆
• Molecular Weight: 411.45
• Mol File: 129046-87-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 138-142℃
• Boiling Point: 617.4 °C at 760 mmHg
• Flash Point: 327.2 °C
• Appearance: /
• Density: 1.251
• Vapor Pressure: 4.21E-16mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BOC-ASP-OFM(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-ASP-OFM(129046-87-3)
• EPA Substance Registry System: BOC-ASP-OFM(129046-87-3)

Safety Data

• Hazardous Substances Data: 129046-87-3(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Boc-Asp-OFm, is an aspartic acid derivative, that can be used in various chemical synthesis and peptide chemistry.

InChI:InChI=1/C23H25NO6/c1-23(2,3)30-22(28)24-19(12-20(25)26)21(27)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,26)/t19-/m0/s1

Upstream product

• 13726-67-5 Boc-Asp-OH 
• 24424-99-5 di-tert-butyl dicarbonate 
• 24324-17-2 9-Fluorenylmethanol 
• 91240-51-6 N-tert-butyloxycarbonylaspartic acid anhydride 

Downstream Products

• 939403-15-3 N²-(tert-butoxycarbonyl)-N⁴-[2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl-(1-4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranosyl]-L-asparagine fluorenylmethyl ester 

Relevant articles and documents

An unexpected product from attempted reductive etherification of a silyl alcohol with an aldehyde

Reductive etherification, using BiBr3/Et3SiH, between two modified amino acids, one with a silyl alcohol side chain and one with an aldehyde side chain, gave, not the desired bis-amino acid, but a tetrahydrooxazine, in good yield.