129047-38-7

Basic information

• Product Name: 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE
• Synonyms: 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE;4-(4-METHOXYBENZYL)-3-METHOXYBENZALDEHYDE;4-(4-METHOXYBEZYL)-3-METHOXY BENZALDEHYDE;Benzaldehyde, 3-methoxy-4-[(4-methoxyphenyl)methoxy]-;4-(4-Methoxybenzyloxy)-3-Methoxybenzaldehyde
• CAS NO: 129047-38-7
• Molecular Formula: C₁₆H₁₆O₄
• Molecular Weight: 272.3
• Mol File: 129047-38-7.mol
• Article Data: 19

Chemical Properties

• Melting Point: 113-115°C
• Boiling Point: 429.9°Cat760mmHg
• Flash Point: 191.2°C
• Appearance: /
• Density: 1.164g/cm³
• Vapor Pressure: 1.36E-07mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE(129047-38-7)
• EPA Substance Registry System: 3-METHOXY-4-[(4-METHOXYBENZYL)OXY]BENZENECARBALDEHYDE(129047-38-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 129047-38-7(Hazardous Substances Data)

Usage

Description

3-Methoxy-4-[(4-methoxybenzyl)oxy]benzenecarbaldehyde is a versatile benzene derivative with the molecular formula C17H18O4. It features an aldehyde group and two methoxy groups attached to the aromatic ring, contributing to its unique chemical properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
3-Methoxy-4-[(4-methoxybenzyl)oxy]benzenecarbaldehyde is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex organic compounds. Its unique structure allows it to be a key component in the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Methoxy-4-[(4-methoxybenzyl)oxy]benzenecarbaldehyde serves as an intermediate in the production of various agrochemicals, such as pesticides and herbicides. Its chemical properties make it suitable for the creation of effective compounds that can protect crops and enhance agricultural productivity.
Used in Organic Chemistry Research:
3-Methoxy-4-[(4-methoxybenzyl)oxy]benzenecarbaldehyde is used as a precursor in the preparation of heterocyclic compounds, which are important in organic chemistry for their diverse applications and properties. Researchers utilize this compound to explore new synthetic pathways and develop novel compounds with potential applications in various fields.
Used in Biological Activity Studies:
3-Methoxy-4-[(4-methoxybenzyl)oxy]benzenecarbaldehyde has been studied for its potential biological activities, such as antioxidant and anti-inflammatory properties. These studies aim to understand its therapeutic potential and explore its use in the development of treatments for various diseases and conditions.
Overall, 3-Methoxy-4-[(4-methoxybenzyl)oxy]benzenecarbaldehyde is a valuable chemical compound with a wide range of applications in the pharmaceutical, agrochemical, and research industries, as well as in the study of its biological properties.

InChI:InChI=1/C16H16O4/c1-18-14-6-3-12(4-7-14)11-20-15-8-5-13(10-17)9-16(15)19-2/h3-10H,11H2,1-2H3

Upstream product

• 121-33-5 vanillin 
• 824-94-2 p-methoxybenzyl chloride 
• 105-13-5 4-Methoxybenzyl alcohol 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 402573-73-3 3-hydroxy-4-((4-methoxybenzyl)oxy) benzaldehyde 
• 74-88-4 methyl iodide 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 1236355-36-4 (E,E)-4,6-bis-(4'-hydroxy-3'-methoxystyryl)pyrimidine 
• 1236355-46-6 2-methylthio-(E,E)-4,6-bis-(4'-hydroxy-3'-methoxystyryl)pyrimidine 
• 1236355-41-1 2-methoxy-(E,E)-4,6-bis-(3'-hydroxy-4'-methoxystyryl)pyrimidine 
• 1236355-40-0 2-methoxy-(E,E)-4,6-bis-(4'-hydroxy-3'-methoxystyryl)pyrimidine 
• 1396036-95-5 2-methoxy-(E,E)-4,6-bis[4'-methoxy-3'-(4''-methoxybenzyloxy)styryl]pyrimidine 
• 1396036-90-0 2-methoxy-(E,E)-4,6-bis[3'-methoxy-4'-(4''-methoxybenzyloxy)styryl]pyrimidine 
• 1396036-62-6 (E,E)-4,6-bis[3'-methoxy-4'-(4''-methoxybenzyloxy)styryl]pyrimidine 
• 1264752-22-8 (5Z)-4-amino-5-({3-methoxy-4-[(4-methoxybenzyl)oxy]phenyl}methylidene)-1,5-dihydro-2H-imidazol-2-one 
• 1264752-47-7 4-{4-[(E)-(1-ethyl-5-imino-3-methyl-2-oxoimidazolidin-4-ylidene)methyl]-2-methoxyphenoxy}-3-(trifluoromethyl)benzonitrile 
• 1264752-36-4 (5Z)-4-amino-5-{[4-(benzyloxy)-3-methoxyphenyl]methylidene}-1,5-dihydro-2H-imidazol-2-one 
• 1264752-48-8 (4Z)-1-ethyl-5-imino-4-[(3-methoxy-4-{[2-(trifluoromethyl)benzyl]oxy}phenyl)methylidene]-3-methylimidazolidin-2-one 
• 1264751-34-9 4-{4-[(Z)-(1-ethyl-5-imino-2-oxoimidazolidin-4-ylidene)methyl]-2-methoxyphenoxy}naphthalene-1-carbonitrile 
• 1264751-33-8 4-{4-[(Z)-(1-ethyl-5-imino-2-oxoimidazolidin-4-ylidene)methyl]-2-methoxyphenoxy}-3-(trifluoromethyl)benzonitrile 
• 1264751-32-7 4-[(Z)-(1-ethyl-5-imino-2-oxoimidazolidin-4-ylidene)methyl]-2-methoxyphenyl 4-methylbenzenesulfonate 

Relevant articles and documents

HETEROARYL COMPOUNDS AS KINASE INHIBITOR

Provided herein are heteroaryl compounds of formula (I) having activity on a receptor protein tyrosine kinase, wherein R 1, R 2, R 3, A, Q, Z, X and W are set forth in the description, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof.

First Discovery of Novel Pyrido[1,2- a]pyrimidinone Mesoionic Compounds as Antibacterial Agents

Plant bacterial diseases cause tremendous decreases in crop yield and quality, and there is a lack of highly effective and low-risk antibacterial agents. A series of novel pyrido[1,2-a]pyrimidinone mesoionic compounds containing vanillin moieties were synthesized, and the application of these mesoionic compounds as plant antibacterial agents was reported here for the first time. The bioassay results revealed that the mesoionic compounds had good antibacterial activity. Of these compounds, compound 11 showed excellent in vitro activity against Xanthomonas oryzae pv. oryzae, with an EC50 value of 1.1 μg/mL, which was substantially better than that of bismerthiazol (92.7 μg/mL) and thiodiazole copper (105.4 μg/mL). Moreover, greenhouse condition trials indicated that the protective and curative activities of compound 11 against rice bacterial leaf blight were 75.12 and 72.04%, respectively, which were better than those of bismerthiazol (62.24 and 50.83%, respectively) and thiodiazole copper (53.35 and 65.04%, respectively). These results provide a basis for the application of mesoionic vanillin moieties as new antibacterial agents.

Facile and selective deprotection of PMB ethers and esters using oxalyl chloride

Oxalyl chloride, (0.5 equiv) was found to cleave the PMB group from alkyl, aryl PMB ethers, and esters to give corresponding alcohol and acid in good yields. This method offers simple and efficient protocol for the selective deprotection of PMB ether and ester in DCE at ambient temperature.