129079-92-1Relevant academic research and scientific papers
Diastereoisomerically pure fulleropyrrolidines as chiral platforms for the design of optically active liquid crystals
Campidelli, Stephane,Bourgun, Philippe,Guintchin, Boris,Furrer, Julien,Stoeckli-Evans, Helen,Saez, Isabel M.,Goodby, John W.,Deschenaux, Robert
supporting information; experimental part, p. 3574 - 3581 (2010/05/01)
Incorporation of [60]fullerene (C60) within self-organizing systems is conceptually challenging but allows us to obtain materials which combine the characteristics (anisotropy, organization) of condensed mesophases with the properties of C
Stereoselective Synthesis of β-Lactams by Oxidative Coupling of Dianions of Acyclic Tertiary Amides
Kawabata, Takeo,Minami, Tatsuya,Hiyama, Tamejiro
, p. 1864 - 1873 (2007/10/02)
Tertiary amides RCH2CON(R')CH2Z, where Z is an electron-withdrawing group, were converted into dianions by treatment with 2 equiv of n-butyllithium or tert-butyllithium, and the dianions were oxidized with N-iodoosuccinimide (NIS) or a Cu(II) carboxylate to form β-lactams stereoselectively.The stereochemistry of β-lactam formation depends on the oxidant; NIS is cis-selective, whereas Cu(II) is nonselective or slightly trans-selective.A high degree of asymmetric induction in the formation of β-lactams was achieved by using (R)-1-phenylethylamines a chiral auxiliary.This asymmetric ring closure was applied to the preparation of cis-β-lactam 31, an intermediate for the synthesis of the monobactam antibiotic carumonam.
