129083-23-4

Upstream product

• 5470-84-8 4-benzyloxybutanal 
• 129083-18-7 (+/-)-(phenylsulfonyl)(p-tolylsulfinyl)methane 
• 3112-85-4 methylphenylsulfonate 

Downstream Products

• 141088-37-1 Acetic acid (E)-(R)-3-benzenesulfonyl-1-(2-benzyloxy-ethyl)-allyl ester 
• 137764-85-3 (R)-(E)-5-(benzyloxy)-1-(phenylsulfonyl)-1-penten-3-ol 
• 137764-82-0 (S)-(E)-5-(benzyloxy)-1-(phenylsulfonyl)-1-penten-3-ol 
• 133886-58-5 C₂₁H₂₈O₅S 
• 133886-25-6 ((E)-1-Benzenesulfonyl-5-benzyloxy-3-methoxymethoxy-pent-1-enyl)-trimethyl-silane 

Relevant academic research and scientific papers

Stereospecific interconversion between cis and trans 2,3-epoxysulfides

A double inversion of configuration and episulfonium ion intermediates are at the heart of a method for the stereospecific interconversion between cis and trans 2,3-epoxysulfides (see scheme). This method can be used in the stereoselective synthesis of ep

A practical route to (E)-γ-hydroxy-αβ-unsaturated phenyl sulfones

Reaction of enolizable aldehydes with p-tolylsulfinylmethyl phenyl sulfone (1) in the presence of piperidine in acetonitrile gave selectively E-γ-hydroxy-αβ-unsaturated phenyl sulfones (2) in good yields. Reaction from enantiomerically pure sulfoxide 1 gave unsaturated sulfones 2 in moderate optical yields (ee= 10-50%).

Facile synthesis of E-γ-hydroxy-α,β-unsaturated sulfones from aldehydes

Reaction of enolizable aldehydes with p-tolylsulfinylmethyl phenyl sulfone (1), in the presence of piperidine in acetonitrile at 0°C, gave selectively E-γ-hydroxy-α,β-unsaturated phenyl sulfones in good yields.