129084-56-6

Basic information

• Product Name: Z(OMe)-Cys(Tacm)-OH
• Synonyms: Z(OMe)-Cys(Tacm)-OH
• CAS NO: 129084-56-6
• Molecular Weight: 398.48
• Mol File: 129084-56-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Z(OMe)-Cys(Tacm)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z(OMe)-Cys(Tacm)-OH(129084-56-6)
• EPA Substance Registry System: Z(OMe)-Cys(Tacm)-OH(129084-56-6)

Safety Data

• Hazardous Substances Data: 129084-56-6(Hazardous Substances Data)

Upstream product

• 754-10-9 2,2-dimethylpropionamide 
• 66297-46-9 N-hydroxymethyl trimethylacetamide 
• 25474-85-5 4-methoxybenzyloxycarbonyl azide 
• 125700-47-2 S-Trimethylacetamidomethyl-L-cysteine (H-Cys(Tacm)OH) 

Relevant articles and documents

Trimethylacetamidomethyl (Tacm) group, a new protecting group for the thiol function of cysteine

S-Trimethylacetamidomethyl-L-cysteine [Cys(Tacm)] was easily prepared from N-hydroxymethyltrimethyl-acetamide and L-cysteine in trifluoroacetic acid. The S-Tacm group is stable to HF, but cleavable with mercury(II) acetate in trifluoroacetic acid or iodine in aqueous acetic acid. Cys(Tacm) is less susceptible to sulfoxide formation than three related groups, i.e., acetamidomethyl (Acm), benzamidomethyl (Bam) and (2-oxo-1-pyrrolidinyl)methyl (Pym).