1291075-34-7Relevant academic research and scientific papers
Isothiazolones; Thiol-reactive inhibitors of cysteine protease cathepsin B and histone acetyltransferase PCAF
Wisastra, Rosalina,Ghizzoni, Massimo,Maarsingh, Harm,Minnaard, Adriaan J.,Haisma, Hidde J.,Dekker, Frank J.
, p. 1817 - 1822 (2011/05/03)
Isothiazolones and 5-chloroisothiazolones react chemoselectively with thiols by cleavage of the weak nitrogen-sulfur bond to form disulfides. They show selectivity for inhibition of the thiol-dependent cysteine protease cathepsin B and the histone acetylt
