1291079-07-6

Basic information

• Product Name: (R,E)-tert-butyl 1-benzyl-2-(2'-tosylvinyl)pyrrolidine-2-carboxylate
• Synonyms: (R,E)-tert-butyl 1-benzyl-2-(2'-tosylvinyl)pyrrolidine-2-carboxylate
• CAS NO: 1291079-07-6
• Molecular Weight: 441.591
• Mol File: 1291079-07-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,E)-tert-butyl 1-benzyl-2-(2'-tosylvinyl)pyrrolidine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R,E)-tert-butyl 1-benzyl-2-(2'-tosylvinyl)pyrrolidine-2-carboxylate(1291079-07-6)
• EPA Substance Registry System: (R,E)-tert-butyl 1-benzyl-2-(2'-tosylvinyl)pyrrolidine-2-carboxylate(1291079-07-6)

Safety Data

• Hazardous Substances Data: 1291079-07-6(Hazardous Substances Data)

Upstream product

• 2812-46-6 proline tert-butyl ester 
• 13894-21-8 ethynyl p-tolyl sulfone 
• 170642-58-7 (S)-N-benzylproline tert-butyl ester 

Downstream Products

• 161564-07-4 (1-benzyl-2-ethylpyrrolidin-2-yl)methanol 
• 1291079-44-1 (1-benzyl-2-vinylpyrrolidin-2-yl)methanol 
• 1291079-42-9 (R)-tert-butyl 1-benzyl-2-vinylpyrrolidine-2-carboxylate 

Relevant articles and documents

Asymmetric α-2-tosylvinylation of in situ-generated N-2-tosylvinyl proline-derived ammonium ylides

Asymmetric α-2-tosylvinylation of N-substituted proline esters using ethynyl tolyl sulfone as an electrophile was shown to proceed in good yield with high enantioselectivities without the addition of any bases. The reaction proceeds via the formation of N-2-tosylvinyl ammonium ylides.