129108-83-4Relevant academic research and scientific papers
Studies on pyrazines; part 30: Synthesis of aminopyrazines from azidopyrazines
Sato,Matsuura,Miwa
, p. 931 - 934 (2007/10/02)
Azidopyrazines do not undergo reduction by reagents that are effective for the preparation of alkyl- or arylamines from the azides because the heterocyclic azides exist in the bicyclic form of tetrazolo[1,5-a]pyrazines. Nevertheless, the conversion into aminopyrazines was achieved by hydrogenolysis in the presence of ammonium hydroxide and palladium-on-carbon or particularly by reduction with tin(II) chloride in methanolic hydrochloric acid, in 34-87% yields. To elucidate the successful progress of the reaction, the equilibrium of azide-atetrazole was examined by 1H NMR spectroscopy in various solvents.
Pyrolysis of Azidopyrazines
Watanabe, Tokuhiro,Ueda, Ikuko,Hayakawa, Naomi,Kondo, Yasuo,Adachi, Hiroko,et al.
, p. 711 - 716 (2007/10/02)
2,3-Dichloro- and 2,5-dichloropyrazines were treated with sodium azide.The former gave diazidopyrazines and the latter, monoazidomonochloropyrazines.Pyrolysis of 2,3-diazidopyrazines resulted the production of 1,2-dicyanoiminoethanes and that of 2-azido-5
