1291080-87-9

Upstream product

• 1291080-86-8 C₂₁H₂₀BrN 
• 68-12-2 N,N-dimethyl-formamide 
• 583-68-6 2-bromo-p-toluidine 
• 106-49-0 p-toluidine 

Downstream Products

• 1291080-56-2 (S)-dimethyl 1-benzyl-6-methyl-2-phenyl-1,2-dihydroquinoline-3,3(4H)-dicarboxylate 
• 1291080-69-7 dimethyl 2-(2-(dibenzylamino)-5-methylbenzylidene)malonate 

Relevant academic research and scientific papers

Expeditious Synthesis of Multisubstituted Quinolinone Derivatives Based on Ring Recombination Strategy

We achieved a concise construction of 3-substituted quinolinone derivatives based on a ring recombination strategy. In this process, seven transformations involving two types of cyclization proceeded in one pot to afford various quinolinone derivatives in good to excellent chemical yields (up to 98%).

Selective activation of enantiotopic C(sp3)-hydrogen by means of chiral phosphoric acid: Asymmetric synthesis of tetrahydroquinoline derivatives

Chiral phosphoric acid-catalyzed asymmetric C-H functionalization has been achieved. In this process, enantiotopic C(sp3)-hydrogen is selectively activated by chiral phosphoric acid to afford tetrahydroquinoline derivatives with excellent enantioselectivities (up to 97% ee).