Cas 1291103-20-2,4-(4-(3-methoxybenzamido)phenylthio)-N-methylpicolinamide

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Check Digit Verification of cas no

The CAS Registry Mumber 1291103-20-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,9,1,1,0 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1291103-20:
(9*1)+(8*2)+(7*9)+(6*1)+(5*1)+(4*0)+(3*3)+(2*2)+(1*0)=112
112 % 10 = 2
So 1291103-20-2 is a valid CAS Registry Number.

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1291103-20-2Relevant academic research and scientific papers

Synthesis and biological evaluation of novel N-methyl-picolinamide-4-thiol derivatives as potential antitumor agents

Huang, Ting-Ting,Huang, Yun-Chuang,Qing, Xiao-Yu,Xia, Yong,Luo, Xun,Ye, Ting-Hong,Yu, Luo-Ting

, p. 6317 - 6330 (2012/08/28)

A novel series of N-methylpicolinamide-4-thiol derivatives were synthesized and evaluated on human cancer cell lines. Among them, compound 6p displayed potent and broad-spectrum anti-proliferative activities in vitro on some human cancer cell lines, even better than sorafenib. The advanced kinase inhibitory assays showed that compound 6p could selectively inhibit Aurora-B kinase. The biological results were rationalized by the molecular docking study, which indicated the stable interactions of 6p with the Aurora-B kinase.

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