129115-32-8Relevant academic research and scientific papers
SYNTHESIS AND STRUCTURES OF METHYL-SUBSTITUTED 1,2,4,5-TETRAHYDRO-3H-SPIRO(BENZ-2-AZEPINE-3,4'-PIPERIDINES)
Kuznetsov, V.V.,Lantsetov, S.V.,Aliev, A.E.,Varlamov, A.V.,Prostakov, N.S.
, p. 1233 - 1237 (2007/10/02)
Methyl-substituted 1,2,4,5-tetrahydro-3H-spiro(benz-2-azepine-3,4'-piperidines) were obtained by the intramolecular cyclization of 4-allyl-4-N-benzyl(α-phenylethyl)aminopiperidines in a acidic medium.The individual isomers of 1'-benzyl-2',5,5'-trimethyl-1
SYNTHESIS OF 4-ALLYL-4-ARYLAMINOPIPERIDINES AND THEIR TRANSFORMATIONS TO SPIRO
Prostakov, N. S.,Kuznetsov, V. V.,Stashenko, E. E.
, p. 1267 - 1271 (2007/10/02)
It was established that the yields of a 4-allyl-4-aryl-aminopiperidines in the reaction of 4-aryliminopiperidines with allylmagnesium bromide increase significantly if the reaction is carried out in the presence of a crown ether.A number of previously unknown spiro were obtained in the cyclization of 4-allyl-4-arylaminopiperidines in the presence of sulfuric acid.
