129121-46-6

Upstream product

• 129121-50-2 4-(4-fluorophenyl)-methylaniline 
• 129121-51-3 4-(5-methyl-2-thienyl)methylaniline 
• 1135-12-2 p-benzylaniline 

Downstream Products

• 352527-96-9 1-(6-benzyl-2-benzothiazolyl)-3-ethylurea 
• 129120-55-4 (2S,3S)-8-benzyl-2,3-dihydro-5-<2-(dimethylamino)ethyl>-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 
• 129121-25-1 (2S,3S)-3-(2-amino-5-benzylphenyl)thio-2-hydroxy-3-(4-methoxyphenyl)propionic acid 
• 129121-04-6 (2S,5S)-8-benzyl-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 
• 129121-47-7 2-amino-5-benzylbenzenethiol 

Relevant academic research and scientific papers

AGRICULTURAL CHEMICALS

The present invention relates to picolinic acid derivatives that are useful in treating fungal diseases ofplants.

Benzothiazole derivatives

The present invention is directed to a compound of formula (I), racemic-diastereomeric mixtures thereof, optical isomers thereof, prodrugs thereof, isotopes thereof or pharmaceutically-acceptable salts of said compound, isomers, prodrugs and isotopes, wherein the variables are defined herein. The compounds of this invention are useful as inhibitors of serine/threonine and tyrosine kinases. In particular, compounds of this invention are useful as inhibitors of tyrosine kinases that are important in hyperproliferative diseases, especially in cancer and in the process of angiogenesis.

1,5-benzothiazepine derivatives, their preparation and their use in the treatment of cardiovascular disorders

Compounds of formula (I): STR1 in which: R 1 is aryl or aromatic heterocyclic; R 2 and R 3 are hydrogen, alkyl, alkoxy, halogen, phenyl, phenoxy, C 1 -C 6 alkylthio, phenylthio, C 1 -C 6 haloalkyl, cyano or nitro, or together are alkylene optionally containing oxygen; R 4 is hydrogen, aliphatic acyl, cycloalkylcarbonyl, cycloalkoxycarbonyl, aromatic acyl, alkoxycarbonyl or benzyloxycarbonyl; R 5 and R 6 are alkyl; and X is oxygen, sulfur or methylene, have calcium channel blocking activity and can serve for the treatment or prophylaxis of cardiovascular diseases and disorders. They may be prepared by reacting a corresponding compound where R 4 is hydrogen and the aminoethyl group is replaced by hydrogen with a compound providing the aminoethyl group and the, if required, acylating the product.