Welcome to LookChem.com Sign In|Join Free
  • or
(D-PHE12,NLE21,38)-CRF (12-41) (HUMAN, RAT) is a potent peptide hormone that is a modified form of corticotropin-releasing factor (CRF) (12-41). It features substitutions at positions 12, 21, and 38, with D-PHE replacing the native phenylalanine at position 12 and NLE replacing leucine at position 21. This modification results in enhanced stability and improved binding affinity for CRF receptors, making it a significant tool for research in both human and rat models. It is instrumental in studying the neuroendocrine and behavioral effects of CRF and its potential as a therapeutic target for stress-related disorders.

129133-27-3

Post Buying Request

129133-27-3 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

129133-27-3 Usage

Uses

Used in Pharmaceutical Research:
(D-PHE12,NLE21,38)-CRF (12-41) (HUMAN, RAT) is used as a research tool for investigating the physiological and pathological roles of CRF in stress-related disorders. Its enhanced stability and binding affinity make it valuable in understanding the neuroendocrine and behavioral effects of CRF.
Used in Neuroscience:
In the field of neuroscience, (D-PHE12,NLE21,38)-CRF (12-41) (HUMAN, RAT) is utilized as a research compound to explore the mechanisms of action of CRF within the central nervous system, particularly its influence on stress responses and related disorders.
Used in Drug Development:
(D-PHE12,NLE21,38)-CRF (12-41) (HUMAN, RAT) serves as a lead compound in the development of new pharmaceuticals targeting the CRF system, potentially leading to treatments for a range of stress-related conditions.
Used in Behavioral Studies:
In behavioral research, (D-PHE12,NLE21,38)-CRF (12-41) (HUMAN, RAT) is employed to study the effects of CRF on mood, anxiety, and other stress-related behaviors, providing insights into the development of therapeutic interventions for mental health disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 129133-27-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,1,3 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 129133-27:
(8*1)+(7*2)+(6*9)+(5*1)+(4*3)+(3*3)+(2*2)+(1*7)=113
113 % 10 = 3
So 129133-27-3 is a valid CAS Registry Number.

129133-27-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name DPhe12,Nle21?ˉ38-Corticotropin Releasing Factor: 12-41, human, rat

1.2 Other means of identification

Product number -
Other names (DPHE12,NLE21'38)-CORTICOTROPIN RELEASING FACTOR (12-41),HUMAN,RAT

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129133-27-3 SDS

129133-27-3Upstream product

129133-27-3Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 129133-27-3