129139-01-1Relevant academic research and scientific papers
SYNTHESE DANS LA CHIMIE DES PHENANTHRIDINES. III. PREPARATION DE QUELQUES MODELES D'ACIDES ω-(DIAMINO-3,8 PHENANTHRIDINYL-6) CARBOXYLIQUES
Lion, C.,Boukou-Poba, J. P.,Charvy, C.
, p. 171 - 181 (2007/10/02)
New series of ω-(3,8-diamino-6-phenanthridinyl) alkanoic acids are obtained from the acid chloride-esters ROCO(CH2)nCOCl (n =0, 3 to 8; R = Me or Et).Reaction of these with 2-amino-3,8-dicarbethoxyaminobiphenyl leads to the expected 2-acylamino-3,8-dicarbethoxyaminobiphenyls which by cyclization lead to the corresponding methyl or ethyl (3,8-dicarbethoxyamino-6-phenanthridinyl)alkanoates.Quaternarization followed by hydrolysis has been performed to obtain some ω-(3,8-diamino-6-phenanthridinium) alkanoic acid salts.
