129151-77-5Relevant academic research and scientific papers
A convergent synthesis of the [4.4]-spiroacetal-γ-lactones cephalosporolides e and F
Brimble, Margaret A.,Finch, Orla C.,Heapy, Amanda M.,Fraser, John D.,Furkert, Daniel P.,O'Connor, Patrick D.
, p. 995 - 1001 (2011/03/19)
A short convergent synthesis of the fungal metabolites cephalosporolides E and F is reported. The key step makes use of a chelation-controlled Mukaiyama aldol reaction to access the key acyclic spiroacetal precursor with the required syn stereochemistry.
