129156-63-4Relevant academic research and scientific papers
Substituted diarylalkyl amides as calcium channel antagonists
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, (2008/06/13)
The present invention provides compounds that block calcium channels and have the Formula I: The present invention also provides pharmaceutical compositions containing the compounds of Formula I and methods of using them to treat stroke, cerebral ischemia
A simple method for preparation of N-mono- and N,N-di-alkylated α-amino acids
Song,Sercel,Johnson,Colbry,Sun,Roth
, p. 8225 - 8230 (2007/10/03)
Reactions of α-amino acids with ketones under hydrogenation conditions using 20% Pd(OH)2/C as the catalyst gave N-mono-alkylated amino acids in high yields. Reductive methylation of N-mono-alkylated amino acids under the same hydrogenation cond
ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXY-α-METHYL CARBONYL COMPOUNDS BY ALDOL REACTION
Ando, Akira,Shioiri, Takayuki
, p. 4969 - 4988 (2007/10/02)
The enantioselective aldol reactions of ketone lithium enolates with aldehydes mediated chiral lithium amides were extensively investigated.The chiral amino ethers 4a-4l and diamines 16a,b were prepared from α-amino acids.The reaction conditions and the s
