129201-77-0

Upstream product

• 131614-18-1 (1S,3S)-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid 
• 1609-86-5 Tert-butyl isocyanate 
• 50302-58-4 1-Phenyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid 

Downstream Products

• 131534-22-0 2-t-butyl-5-phenyl-3-oxo-6H-2,3,5,11-tetrahydroimidazo<1,5-b>-β-carboline 
• 131534-16-2 2-t-butyl-5-phenyl-6H-1,2,3,5,11,11a-hexahydroimidazo<1,5-b>-β-carboline 

Relevant academic research and scientific papers

Kinesin inhibitors

The present invention provides for compounds, compositions, methods and systems for inhibiting cell growth. More specifically, the present invention provides for methods, compounds and compositions which are capable of inhibiting mitosis in metabolically active cells. Compounds, compositions and methods of the present invention inhibit the activity of a protein involved in the assembly and maintenance of the mitotic spindle. One class of proteins which acts on the mitotic spindle is the family of mitotic kinesins, a subset of the kinesin superfamily.

Synthesis and Reactivity of &β-Carboline-hydantoin Systems

The synthesis of 2,5-disubstituted 1,3-dioxo-6H-1,2,3,5,11,11a-hexahydroimidazo-β-carbolines 3a-y and the reduction of -carbolines 3m-r with different amounts of lithium aluminium hydride is described.