129211-95-6Relevant academic research and scientific papers
Aromatic isothiazolopyridines: New direct synthetic approaches
Chimichi,Giomi,Tedeschi,Ponticelli
, p. 73 - 78 (2007/10/02)
Alternative synthetic route to the title ring systems were examined: the isothiazolopyridines 5a,b and 10 were obtained by single step procedures from pyridine derivatives.
Synthetic Investigation on Isothiazolo-- and --pyridines
Chimichi, Stefano,Nesi, Rodolfo,Ponticelli, Fabio,Tedeschi, Piero
, p. 1477 - 1480 (2007/10/02)
Different approaches to the title ring systems were examined, based on the cleavage of the N-O bond in the isoxazolopyridine-4-thiols (3) and (4) which afforded the hydroxy derivatives (6) and (7), respectively, in moderate to good yields. 3-Methylisothiazolo-- and --pyridine (11) and (18), as well as several functionalized derivatives, were easily obtained from these key intermediates through the corresponding 4,6-dichloroisothiazolopyridines (10) and (17).
