129211-96-7Relevant academic research and scientific papers
Synthetic Investigation on Isothiazolo-- and --pyridines
Chimichi, Stefano,Nesi, Rodolfo,Ponticelli, Fabio,Tedeschi, Piero
, p. 1477 - 1480 (2007/10/02)
Different approaches to the title ring systems were examined, based on the cleavage of the N-O bond in the isoxazolopyridine-4-thiols (3) and (4) which afforded the hydroxy derivatives (6) and (7), respectively, in moderate to good yields. 3-Methylisothiazolo-- and --pyridine (11) and (18), as well as several functionalized derivatives, were easily obtained from these key intermediates through the corresponding 4,6-dichloroisothiazolopyridines (10) and (17).
