129217-85-2

Basic information

• Product Name: trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane
• Synonyms: trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane
• CAS NO: 129217-85-2
• Molecular Weight: 238.21
• Mol File: 129217-85-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 235.2±23.0 °C(Predicted)
• Density: 0.90±0.1 g/cm3(Predicted)
• CAS DataBase Reference: trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane(129217-85-2)
• EPA Substance Registry System: trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane(129217-85-2)

Safety Data

• Hazardous Substances Data: 129217-85-2(Hazardous Substances Data)

Upstream product

• 6224-91-5 trimethyl(prop-1-ynyl)silane 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 1198785-55-5 5-fluoro-2-((S)-4-hydroxy-2-methyl-4-(trifluoromethyl)hept-6-yn-2-yl)-N-((S)-1-(4-methoxyphenyl)ethyl)benzamide 
• 6224-91-5 trimethyl(prop-1-ynyl)silane 
• 14657-22-8 allenyltrimethylsilane 
• 38002-45-8 3-bromo-1-(trimethylsilyl)-1-propyne 
• 38002-44-7 1-bromo-1-(trimethylsilyl)propadiene 
• 1202493-66-0 C₁₄H₁₇F₃OSi 
• 1312791-27-7 2-(4-chlorophenyl)-5-(trimethylsilyl)pent-4-yn-2-ol 
• 67448-60-6 1-methyl-1-phenyl-4-(trimethylsilyl)-3-butyn-1-ol 
• 1202493-62-6 C₁₅H₂₀O₃Si 
• 1202493-63-7 C₁₇H₂₆O₂Si 
• 79015-64-8 1-cyclohexyl-4-trimethylsilanyl-but-3-yn-1-ol 
• 1204403-78-0 trimethyl[(E)-6-phenylhexa-1,2,5-trien-3-yl]silane 
• 1228758-51-7 C₁₇H₂₅NO₃Si 
• 1228758-43-7 C₁₇H₂₄O₄Si 

Relevant articles and documents

Preparative synthesis via continuous flow of 4,4,5,5-tetramethyl-2-(3- trimethylsilyl-2-propynyl)-1,3,2-dioxaborolane: A general propargylation reagent

A scalable process for the preparation of 4,4,5,5-tetramethyl-2-(3- trimethylsilyl-2-propynyl)-1,3,2-dioxaborolane from trimethylsilylpropyne, isopropyl pinacol borate, and n-butyllithium is described. Problems associated with implementing a typical aqueous workup and batch process into production due to borolane ate equilibration and protonolysis are presented. To address these issues, a continuous-flow and distillation process was developed which efficiently produced 297 kg of the key propargylation reagent.

NHC-Cu-catalyzed addition of propargylboron reagents to phosphinoylimines. Enantioselective synthesis of trimethylsilyl-substituted homoallenylamides and application to the synthesis of S-(-)-cyclooroidin

A catalytic method for the efficient and enantioselective addition of a 1-trimethylsilyl-substituted allene moiety to phosphinoylimines is presented. Transformations are promoted by 5.0 mol % of a copper complex of an N-heterocyclic carbene in the presenc

STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS

A process for synthesis of a compound of Formula (X) wherein R1 is an aryl group substituted with one to three substituent groups, wherein each substituent group of R1 is independently C1-C5 alkyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, halogen, carboxy, cyano, or trifluoromethyl, wherein each substituent group of R1 is optionally independently substituted with one to three substituents selected from C1-C3 alkyl, C1-C3 alkoxy, phenyl, and alkoxyphenyl; and R2 and R3 are each independently C1-C5 alkyl.