1292296-50-4Relevant academic research and scientific papers
Atom-economical route to substituted pyridines via a scandium imide
Wicker, Benjamin F.,Scott, Jennifer,Fout, Alison R.,Pink, Maren,Mindiola, Daniel J.
, p. 2453 - 2456 (2011)
Taking advantage of a tautomerization process between (PNP)Sc - N(DIPP)(NC5H5) (PNP = N[2-P(CHMe2) 2-4-methylphenyl]2-, DIPP = 2,6-iPr 2C6H3) and (PNP)Sc(NH(DIPP))(η2- NC5H4) (1), we demonstrate in this work that pyridine can be both activated and functionalized with isonitriles (in one case catalytically) to ultimately afford mono- and bis-imino-substituted pyridines. Several intermediates in the cycle have been isolated and characterized.
