1292320-56-9Relevant academic research and scientific papers
Towards more specific O6-methylguanine-DNA methyltransferase (MGMT) inactivators
Lopez, Sergio,Margison, Geoffrey P.,Stanley McElhinney,Cordeiro, Alessandra,McMurry, T. Brian H.,Rozas, Isabel
experimental part, p. 1658 - 1665 (2011/04/16)
Searching for a novel family of inactivators of the human DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) which is known to bind to the DNA minor groove, we have computationally modelled and synthesised two series of 2-amino-6-
