1292322-08-7

Upstream product

• 1292321-47-1 C₂₉H₃₄F₂N₂O₅ 
• 1292321-48-2 C₂₂H₂₃F₂NO₄ 
• 1292321-49-3 C₁₈H₂₆F₂N₂O₂ 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 135716-08-4 tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate 
• 135716-09-5 tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 
• 161315-55-5 3-[2-(N-t-BOC-4-piperidinyl)-1-oxoethyl]-4(R)-(benzyl)-2-oxazolidinone 

Relevant academic research and scientific papers

Synthesis and evaluation of [(1R)-1-amino-2-(2,5-difluorophenyl)ethyl] cyclohexanes and 4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]piperidines as DPP-4 inhibitors

A series of 4-amino cyclohexanes and 4-substituted piperidines were prepared and evaluated for inhibition of DPP-4. Analog 20q displayed both good DPP-4 potency and selectivity against other proteases, while derivative 20k displayed long half life and mod