1292324-66-3

Basic information

• Product Name: (R)-4-aMinopyrrolidin-2-one hydrochloride
• Synonyms: (R)-4-aMinopyrrolidin-2-one hydrochloride;2-Pyrrolidinone, 4-aMino-, (4R)-;(4R)-4-Amino-2-pyrrolidinone;(R)-4-amino-pyrrolidin-2-one;(4R)-4-Aminopyrrolidin-2-one dihydrochloride;(R)-4-AMINOPYRROLIDIN-2-ONE HCL
• CAS NO: 1292324-66-3
• Molecular Formula: C4H8N2O
• Molecular Weight: 100.11912
• Mol File: 1292324-66-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-4-aMinopyrrolidin-2-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-aMinopyrrolidin-2-one hydrochloride(1292324-66-3)
• EPA Substance Registry System: (R)-4-aMinopyrrolidin-2-one hydrochloride(1292324-66-3)

Safety Data

• Hazardous Substances Data: 1292324-66-3(Hazardous Substances Data)

Usage

General Description

(R)-4-aminopyrrolidin-2-one hydrochloride is a chemical compound that is used in the synthesis of various pharmaceutical drugs and other organic compounds. It is a hydrochloride salt form of (R)-4-aminopyrrolidin-2-one, which is a chiral compound with potential therapeutic applications. This chemical is a white to off-white crystalline powder that is soluble in water and other polar solvents. It is also known by its CAS number 51116-01-3 and is used as a reagent in organic synthesis and as a building block in the production of various pharmaceutical intermediates.

Upstream product

• 899806-32-7 (S)-4-azidopyrrolidin-2-one 
• 1346773-63-4 [(3R)-5-oxopyrrolidin-3-yl]carbamic acid tert-butyl ester 

Downstream Products

• 1443929-80-3 C₁₁H₁₂N₂O₂S 

Relevant articles and documents

PYRROLIDINE DERIVATIVES WITH ANTIBACTERIAL PROPERTIES

Provided is a compound of Formula (I) or a salt thereof: Formula (I) wherein R, m, n, R1, R2, Aa-Ac are defined as in the claims and ArI represents a bicyclic heterocyclic group of the following formula: Formula (2) Ar 2 represents a bicyclic heterocyclic group of the formula: [Formula 3] having antibacterial activity.

Synthesis of (R)-3,4-diaminobutanoic acid by desymmetrization of dimethyl 3-(benzylamino)glutarate through enzymatic ammonolysis

Lipase B from Candida antarctica is shown to be a highly efficient catalyst for the desymmetrization of dimethyl 3-(benzylamino)glutarate (1) through aminolysis and ammonolysis reactions. Using this procedure, enantiopure monoamides are obtained in high yield. The synthetic value of these compounds is demonstrated by the preparation of an enantiopure nonnatural amino acid, i.e. (R)-3,4-diaminobutanoic acid [(+)-12].