129276-14-8Relevant academic research and scientific papers
The Phthalimidomethyl Rearrangement
Wilshire, John F. K.
, p. 1817 - 1826 (2007/10/02)
The discovery of a new acid-catalysed monodentate N -> C aromatic rearrangement, namely the phthalimidomethyl rearrangement, is reported.In this rearrangement, discovered during the reaction of N-hydroxymethylphthalimide with certain alkyl N-(4-nitrophenyl)carbamates in concentrated sulfuric acid solution, the phthalimidomethyl group migrates from its initial location on the nitrogen atom of the carbamate function to a carbon atom of the nitrophenyl group.Evidence, provided by an appropriate 'crossover' experiment, indicates that the rearrangement is intermolecular.Hindered rotation about the N(carbamoyl)-aryl bond of the N-phthalimidomethyl derivatives of both ethyl and methyl N-(2,4-dinitrophenyl)carbamate is reported.
A Comparison of the Reactions of Some Ethyl N-Arylcarbamates with Those of the Corresponding Acetanilides. II Amidomethylation with N-Hydroxymethylphthalimide
Rosevear, Judi,Wilshire, John F. K.
, p. 339 - 353 (2007/10/02)
The reactions of some ethyl N-arylcarbamates and of the corresponding acetanilides towards 1 equiv. of N-hydroxymethylphthalimide in concentrated sulfuric acid at 50 deg C have been compared with one another.In the case of certain para-substituted compoun
