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Asperfuran is a fungal metabolite originally isolated from A. oryzae that possesses antifungal and anticancer activities. It is known for its ability to inhibit the growth of various fungi and cancer cells, making it a potential candidate for pharmaceutical applications.

129277-10-7

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129277-10-7 Usage

Uses

Used in Antifungal Applications:
Asperfuran is used as an antifungal agent for its ability to inhibit the growth of 23 fungi in a disc assay when used at a concentration of 50 μg per disc. Its antifungal properties make it a promising candidate for treating fungal infections.
Used in Anticancer Applications:
Asperfuran is used as an anticancer agent for its ability to inhibit the proliferation of HeLa S3 and L1210 cancer cells with IC50 values of 25 μg/ml for both. Its anticancer properties make it a potential candidate for developing cancer treatments.
Used in Enzyme Inhibition:
Asperfuran is used as an inhibitor of chitin synthase, an enzyme involved in the synthesis of chitin, a major component of fungal cell walls. It inhibits chitin synthase with an IC50 value of 300 μM, making it a potential candidate for targeting fungal infections by disrupting chitin synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 129277-10-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,2,7 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 129277-10:
(8*1)+(7*2)+(6*9)+(5*2)+(4*7)+(3*7)+(2*1)+(1*0)=137
137 % 10 = 7
So 129277-10-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H14O3/c1-2-3-4-5-9-8-16-13-11(9)6-10(14)7-12(13)15/h3,5-7,9,14-15H,2,8H2,1H3

129277-10-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-penta-1,2-dienyl-2,3-dihydro-1-benzofuran-5,7-diol

1.2 Other means of identification

Product number -
Other names 5,7-Benzofurandiol,2,3-dihydro-2-(1E,3E)-1,3-pentadien-1-yl-,(2R)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129277-10-7 SDS

129277-10-7Upstream product

129277-10-7Downstream Products

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