1292770-19-4Relevant academic research and scientific papers
Three-component synthesis of dialkyl 2-(cyclohexyliminomethylene)-3- arylsulfonylamino succinate
Anaraki-Ardakani, Hossein,Mosslemin, Mohammad Hossein,Sadoughi, Hesamaddin,Makvandi, Nima
, p. 98 - 100 (2011)
The reactive 1:1 intermediate produced in the reaction between cyclohexyl isocyanide and dialkyl acetylenedicarboxylates was trapped by arylsulfonamides to yield highly functionalised stable ketenimines under mild reaction conditions in fairly good yields
An environmentally benign approach for the synthesis of bifunctional sulfonamide-amide compounds via isocyanide-based multicomponent reactions
Shaabani, Ahmad,Sarvary, Afshin,Ghasemi, Sabrieh,Rezayan, Ali Hossein,Ghadari, Rahim,Ng, Seik Weng
supporting information; experimental part, p. 582 - 585 (2011/05/06)
Three-component reaction of the zwitterion generated from dialkyl acetylenedicarboxylate and an alkyl or aryl isocyanide with an alkyl or aryl sulfonamide is described. The reaction afforded the corresponding special type of ketenimine sulfonamide derivatives in water without using any activation and modification. The products could be easily hydrolyzed to the corresponding sulfonamide-butanamide derivatives at 80 °C in good yields without using a catalyst. The Royal Society of Chemistry.
A two-step synthesis of 1,5-disubstituted tetrazoles containing a siloxy or sulfonamide group
Sarvary, Afshin,Shaabani, Shabnam,Shaabani, Ahmad,Ng, Seikweng
scheme or table, p. 5930 - 5933 (2011/11/29)
A simple two-step route to the synthesis of 1,5-disubstituted tetrazoles containing a β-siloxy or β-sulfonamide group is presented. The synthesis takes place via an isocyanide-based multicomponent reaction and allows incorporation of a wide variety of substitution patterns starting from commercially available reagents. This is followed by cyclization of the ketenimines with trimethylsilyl azide without using any catalyst or activation.
