1292770-20-7Relevant academic research and scientific papers
An environmentally benign approach for the synthesis of bifunctional sulfonamide-amide compounds via isocyanide-based multicomponent reactions
Shaabani, Ahmad,Sarvary, Afshin,Ghasemi, Sabrieh,Rezayan, Ali Hossein,Ghadari, Rahim,Ng, Seik Weng
, p. 582 - 585 (2011)
Three-component reaction of the zwitterion generated from dialkyl acetylenedicarboxylate and an alkyl or aryl isocyanide with an alkyl or aryl sulfonamide is described. The reaction afforded the corresponding special type of ketenimine sulfonamide derivatives in water without using any activation and modification. The products could be easily hydrolyzed to the corresponding sulfonamide-butanamide derivatives at 80 °C in good yields without using a catalyst. The Royal Society of Chemistry.
Three-component synthesis of dialkyl 2-(cyclohexyliminomethylene)-3- arylsulfonylamino succinate
Anaraki-Ardakani, Hossein,Mosslemin, Mohammad Hossein,Sadoughi, Hesamaddin,Makvandi, Nima
experimental part, p. 98 - 100 (2011/07/07)
The reactive 1:1 intermediate produced in the reaction between cyclohexyl isocyanide and dialkyl acetylenedicarboxylates was trapped by arylsulfonamides to yield highly functionalised stable ketenimines under mild reaction conditions in fairly good yields
