1292780-40-5Relevant articles and documents
Oxindole derivatives as inhibitors of TAK1 kinase
Lockman, Jeffrey W.,Reeder, Matthew D.,Robinson, Rosann,Ormonde, Patricia A.,Cimbora, Daniel M.,Williams, Brandi L.,Willardsen, J. Adam
, p. 1724 - 1727 (2011/05/04)
Several series of oxindole analogues were synthesized and screened for inhibitory activity against transforming growth factor-β-activating kinase 1 (TAK1). Modifications around several regions of the lead molecules were made, with a distal hydroxyl group