1292785-60-4Relevant academic research and scientific papers
Synthesis of functionalized arylpyridines and -pyrimidines by domino [4+2]/retro [4+2] cycloadditions of electron-rich dienes with alkynylpyridines and -pyrimidines
Abid, Obaid-Ur-Rahman,Nawaz, Muhammad,Ibad, Muhammad Farooq,Khera, Rasheed Ahmad,Iaroshenko, Viktor,Langer, Peter
experimental part, p. 2185 - 2191 (2011/04/26)
Aryl-substituted pyridines and pyrimidines were prepared by [4+2] cycloadditions of alkynyl-substituted pyridines and -pyrimidines with electron-rich dienes. The reactions proceed by formation of a bridged cycloadduct and subsequent thermal extrusion of ethylene. The pyridine moiety plays a crucial role for the success of the reaction.
