1292813-15-0Relevant academic research and scientific papers
Iminofuran chemistry: VII. Intramolecular cyclization of 2-N-aryl-substituted derivatives of 2-amino-4-aryl-4-oxobut-2-enoic and 2-amino-5,5-dimethyl4-oxohex-2-enoic acids
Tyuneva,Igidov,Koryagina,Borodin, A. Yu.,Zakhmatov,Makarov,Toksarova, Yu. C.,Rubtsov
, p. 258 - 264 (2011)
The cyclization at the treatment of acetic anhydride of 4-aryl-2-arylamino-4-oxobut-2-enoic and 2-arylamino-5,5-dimethyl-4-oxohex-2- enoic acids was investigated furnishing derivatives of 5-aryl-3-aryl-imino-3H- furan-2-ones and 4-arylamino-2-tert-butyl-2,5-dihydro-5-oxofuran-2-yl acetate respectively. 2-N2-Methylenesubstituted 4-aryl-2-hydrazino-4-oxobut- 2-enoic and 5,5-dimethyl-2-hydrazino-4-oxohex-2-enoic acids cleanly underwent cyclization under the effect of acetic anhydride into 5-aryl-3-hydrazono-3H- furan-2-ones and 5-tert-butyl-3-hydrazono-3H-furan-2-ones.
