129286-73-3Relevant articles and documents
Lattice-controlled Norrish III Cleavage of Crystalline Methadone
Reisch, Gisela,Reisch, J.
, p. 402 - 404 (2007/10/02)
The photochemical cleavage of crystalline D-(-)-methadone yields 3-dimethylamino-1,1-diphenylbut-1-ene and propionaldehyde.Abstraction of beta hydrogen (Norrish III cleavage) by the electronically activated carbonyl oxygen induces this process which involves a five-membered cyclic transition type that is preformed by the conformation fixed in the lattice.It can be attributed to a reaction of zero order.