129287-63-4

Upstream product

• 109-72-8 n-butyllithium 
• 118356-63-1 (E,2R,6R)-5-Benzyliden-2-tert-butyl-6-methyl-1,3-dioxan-4-on 
• 107289-12-3 (1'RS,2R,5R,6R)-2-(tert-butyl)-5-(α-hydroxybenzyl)-6-methyl-1,3-dioxan-4-one 

Downstream Products

• 129287-80-5 (1'R,2R,3S)-2-(1'-Hydroxyethyl)-3-phenylheptansaeure 
• 61999-35-7 (S)-(+)-3-phenylheptanoic acid 
• 69657-31-4 (S)-3-Phenyl-heptanoic acid methyl ester 

Relevant academic research and scientific papers

(E,R,R)-5-Alkylidene-2-tert-butyl-6-methyl-1,3-dioxan-4-ones: Preparation from (R)-3-Hydroxybutbutyric Acid, Cuprate Additions and Hydrolyses to 3-Hydroxycarboxylic Acids with Chiral Secondary Alkyl Substituents in the 2-Position

Li enolates of (R,R)-2-tert-Butyl-6-methyl-1,3-dioxan-4-one add to aliphatic or aromatic aldehydes with relative topicity Re,Re (2:1 to 10:1, 9 examples).The title compounds are obtained from these aldol adducts by dehydration through mesylates (5 example