129288-91-1Relevant articles and documents
Synthesis and bioactivity of erythromycin derivatives
Chen, Mingwei,Muri, Estela M. F.,Jacob, Melissa,Williamson, John S.
, p. 111 - 129 (2007/10/03)
A small series of semi-synthetic 6-O-alkylated erythro mycin derivatives were synthesized and evaluated for their antimicrobial activity. A dichlorobenzenyl 6-O-allyl erythromycin derivative, 11a was found to be active against Cryptococcus neoformans (IC50 5.0 μg/mL), Staphylococcus aureus (IC50 5.0 μg/mL), and methicillin-resistant Staphlococcus aureus (IC50 5.0 μg/mL).