129320-01-0

Upstream product

• 20766-36-3 (E)-4-(3-chlorophenyl)but-3-en-2-one 
• 587-04-2 m-Chlorobenzaldehyde 
• 129319-77-3 [(E)-3-(3-Chloro-phenyl)-1-methyl-allyl]-carbamic acid tert-butyl ester 

Downstream Products

• 1289142-61-5 (R,E)-N-(4-(3-chlorophenyl)but-3-en-2-yl)benzamide 
• 1289142-89-7 (S,E)-N-(4-(3-chlorophenyl)but-3-en-2-yl)benzamide 

Relevant academic research and scientific papers

A dual-catalysis/anion-binding approach to the kinetic resolution of allylic amines

Chemical equations presented. A dual-catalysis approach enables the small-molecule catalyzed kinetic resolution of allylic amines by acylation. By employing 2 mol % of each 4-(pyrrolidino)pyridine (PPY) and a readily available chiral hydrogen-bonding coca

WITTIG OLEFINATION IN THE ABSENCE OF AN EXOGENOUS BASE: A NEW SYNTHESIS OF α-SUBSTITUTED PRIMARY ALLYLIC AMINES

A new synthesis of α-substituted primary allylic amines through the in situ generation and trapping of an ylide from the reaction of an N-acyl aziridine, triphenylphosphine, and an aldehyde in refluxing isopropanol is reported.These compounds can be prepared enantioselectively (> 94.6percent ee) by employing a chiral nonracemic N-acyl aziridine.