1293285-67-2Relevant academic research and scientific papers
Synthesis and biological evaluation of unsaturated keto and exomethylene d-arabinopyranonucleoside analogs: Novel 5-fluorouracil analogs that target thymidylate synthase
Tzioumaki, Niki,Manta, Stella,Tsoukala, Evangelia,Voorde, Johan Vande,Liekens, Sandra,Komiotis, Dimitri,Balzarini, Jan
, p. 993 - 1005 (2011/04/17)
The synthesis of pyrimidine unsaturated keto and exomethylene arabinopyranonucleoside analogs as potential antitumor and antiviral agents is described. Commercially available 1,2,3,4-tetra-O-acetyl-d-arabinopyranose (1) was condensed with silylated thymin
