1293285-86-5

Basic information

• Product Name: 4-fluoro-2-(pyrimidin-2-yl)benzonitrile
• Synonyms: 4-fluoro-2-(pyrimidin-2-yl)benzonitrile
• CAS NO: 1293285-86-5
• Molecular Weight: 199.187
• Mol File: 1293285-86-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-fluoro-2-(pyrimidin-2-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluoro-2-(pyrimidin-2-yl)benzonitrile(1293285-86-5)
• EPA Substance Registry System: 4-fluoro-2-(pyrimidin-2-yl)benzonitrile(1293285-86-5)

Safety Data

• Hazardous Substances Data: 1293285-86-5(Hazardous Substances Data)

Upstream product

• 119072-55-8 tert-butylisonitrile 
• 68049-16-1 2-(3-fluorophenyl)-pyrimidine 
• 1031929-20-0 2-iodo-4-fluorobenzonitrile 
• 153435-63-3 2-(tributylstannyl)pyrimidine 

Downstream Products

• 1293285-88-7 4-methoxy-2-(pyrimidin-2-yl)benzoic acid 
• 1293285-84-3 4-fluoro-2-(pyrimidin-2-yl)benzoic acid 

Relevant articles and documents

Rhodium-catalyzed direct C-H bond cyanation of arenes with isocyanide

An efficient rhodium-catalyzed regioselective C-H bond cyanation of arenes was developed using tert-butyl isocyanide as the cyanide source. A wide range of (hetero)aryl and cycloalkenyl nitriles could be afforded with high regioselectivity and good functional group tolerance.

FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS

Certain disubstituted 3,8-diaza-bicyclo[4.2.0]octane and 3,6-diazabicyclo [3.2.0]heptane are described, which are useful as orexin inhibitors. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.