1293326-49-4Relevant articles and documents
2,6-Bis(phenylethynyl)biphenyls and their cyclization to pyrenes
MacHuy, Mareike M.,Wuertele, Christian,Schreiner, Peter R.
experimental part, p. 1405 - 1409 (2012/07/02)
We present a new protocol for pyrene synthesis via transition-metal cross-couplings. The initially prepared 2,6-bis(phenylethynyl)biphenyls were transformed to pyrenes with uncommon 4,10-disubstitution through an electrophilic cyclization. The precursors were synthesized by Suzuki-Miyaura cross-coupling, which provides 2,6-dibromobiphenyls; these were subsequently coupled with phenylethynyl derivatives via Kumada cross-coupling. Georg Thieme Verlag Stuttgart · New York.