129341-01-1Relevant academic research and scientific papers
1,2-diastereoselection induced by chiral silicon in the addition of Grignard reagents to acylsilanes
Bonini, Bianca F.,Masiero, Stefano,Mazzanti, Germana,Zani, Paolo
, p. 6801 - 6804 (2007/10/02)
The reaction of acylsilanes 1 with Grignard reagents gives the diastereomeric α-hydroxysilanes 3. The level of asymmetric induction depends on the nature of R1 and R2. Good results were obtained for R1=t-Bu, R2=
Synthese von racemischem Acetyl(t-butyl)methylphenylsilan und Acetylmethylphenylsilan: Substrate fuer stereoselektive mikrobielle Reduktionen
Tacke, Reinhold,Fritsche, Kirsten,Tafel, Andrea,Wuttke, Frank
, p. 47 - 55 (2007/10/02)
The racemic acetyltriorganylsilanes MePh(Me3C)SiC(O)Me (1) and MePh(Me3SiCH2)SiC(O)Me (2) were prepared from MePhSiCl2.Compounds 1 and 2 are available by two different three-step synthesis.Method a: MePhSiCl2 -> MePh(Me3C)SiCl (5) -> (7) -> 1 (t
