1293894-82-2Relevant academic research and scientific papers
Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity
Chorell, Erik,Bengtsson, Christoffer,Sainte-Luce Banchelin, Thomas,Das, Pralay,Uvell, Hanna,Sinha, Arun K.,Pinkner, Jerome S.,Hultgren, Scott J.,Almqvist, Fredrik
, p. 1103 - 1116 (2011/04/22)
Pilicides are a class of compounds that attenuate virulence in Gram negative bacteria by blocking the chaperone/usher pathway in Escherichia coli. It has also been shown that compounds derived from the peptidomimetic scaffold that the pilicides are based
