1293914-06-3Relevant academic research and scientific papers
Cocrystals of 2,3,5,6-tetra-fluoro-benzene-1,4-diol with diaza aromatic compounds
Czapik, Agnieszka,Gdaniec, Maria
experimental part, p. o356-o360 (2010/10/03)
2,3,5,6-Tetra-fluoro-benzene-1,4-diol easily forms cocrystals with heteroaromatic bases containing the pyrazine unit. In the 1:1 complexes with pyrazine, C6H246O2·C 4H4N2, (I), and quinoxaline, C 6H2F4O2·C8H 6N2, (II), the crystal components are linked via O - H...N hydrogen bonds into one-dimensional chains. With the largest base, phenazine, the 1:2 benzenediol-phenazine complex, C6H 2F4O2·2C12H8N 2, (III), was obtained, with the mol-ecules linked via O - H...N inter-actions into a discrete heterotrimer. In all three cocrystals, the two types of mol-ecules are organized into layers via softer C - H...O and C - H...F inter-actions and π-π stacking inter-actions, with stronger hydrogen bonds linking mol-ecules of adjacent layers. In (II) and (III), mol-ecules are arranged into heterostacks, whereas in (I) separate stacks are formed by the heterocyclic base and the benzene-diol molecule.
