1293937-66-2Relevant academic research and scientific papers
Handling Hazards Using Continuous Flow Chemistry: Synthesis of N1-Aryl-[1,2,3]-triazoles from Anilines via Telescoped Three-Step Diazotization, Azidodediazotization, and [3 + 2] Dipolar Cycloaddition Processes
Teci, Matthieu,Tilley, Michael,McGuire, Michael A.,Organ, Michael G.
, p. 1967 - 1973 (2016)
The conversion of commercially available anilines into triazole products was realized using a telescoped three-reactor flow diazotization, azidodediazotization, and [3 + 2] dipolar cycloaddition process. The diazotization-azidodediazotization sequence was
A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3- triazoles
Smith, Catherine J.,Nikbin, Nikzad,Ley, Steven V.,Lange, Heiko,Baxendale, Ian R.
, p. 1938 - 1947 (2011/04/24)
Having demonstrated in the preceding publication the flow synthesis of aryl azides, we describe here a general protocol for the in-line purification of these versatile intermediates. As part of this investigation, we evaluated the use of ReactIR 45m as a
