1293941-36-2Relevant academic research and scientific papers
A simple and efficient synthesis of 9-arylfluorenes via metal-free reductive coupling of arylboronic acids and N-tosylhydrazones in situ
Shen, Xu,Gu, Ningning,Liu, Ping,Ma, Xiaowei,Xie, Jianwei,Liu, Yan,He, Lin,Dai, Bin
, p. 63726 - 63731 (2015)
A general, yet efficient synthesis method of 9-arylfluorenes via metal-free reductive coupling of N-tosylhydrazones and arylboronic acids has been developed. This methodology is realized by a one-pot protocol in two steps involving the preparation of N-tosylhydrazones by reacting tosylhydrazide with 9-fluorenone derivatives, followed by the reductive coupling of arylboronic acid in the presence of potassium carbonate to afford various 9-arylfluorenes analogues in moderate to excellent yields. Importantly, the catalytic system presented here enables the use of easily accessible starting materials and can be employed on a wide variety of substrates with good functional group tolerance. This protocol could also be particularly useful for the synthesis of 9-fluorenyl-substituted carbazolyl compounds.
Substituted diaryldiazomethanes and diazofluorenes: Structure, reactivity and stability
Davis, Philip J.,Harris, Lawrence,Karim, Aman,Thompson, Amber L.,Gilpin, Martin,Moloney, Mark G.,Pound, Matthew J.,Thompson, Claire
supporting information; experimental part, p. 1553 - 1556 (2011/04/26)
The synthesis of several substituted diaryldiazomethanes and diazofluorenes, and an assessment of their structure, reactivity and stability, is reported.
