129398-32-9Relevant academic research and scientific papers
First synthesis of totally orthogonal protected α-(trifluoromethyl)- and α-(difluoromethyl)arginines
Moroni,Koksch,Osipov,Crucianelli,Frigerio,Bravo,Burger
, p. 130 - 133 (2007/10/03)
The first synthesis of a series of totally orthogonal protected racemic α-(trifluoromethyl)- and α-(difluoromethyl)arginines is described. The key steps of the synthesis are the mild guanidinylation procedure and the selective hydrogenation of a CC triple bond in the presence of a Cbz-group.
