129414-88-6

Basic information

• Product Name: KRIBB 3
• Synonyms: KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole)
• CAS NO: 129414-88-6
• Molecular Formula: C19H19NO4
• Molecular Weight: 325.362
• Mol File: 129414-88-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 147-148 °C
• Boiling Point: 467.5±45.0 °C(Predicted)
• Appearance: /
• Density: 1.181±0.06 g/cm3(Predicted)
• Refractive Index: 1.61
• Storage Temp.: −20°C
• PKA: 8.51±0.48(Predicted)
• CAS DataBase Reference: KRIBB 3(CAS DataBase Reference)
• NIST Chemistry Reference: KRIBB 3(129414-88-6)
• EPA Substance Registry System: KRIBB 3(129414-88-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN 2811 6.1/PG 3
• Hazardous Substances Data: 129414-88-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H19NO4/c1-4-12-9-15(17(21)10-18(12)23-3)19-16(11-20-24-19)13-5-7-14(22-2)8-6-13/h5-11,20H,4H2,1-3H3/b19-15-

Upstream product

• 37470-83-0 5-ethyl-2,4-dihydroxy-benzaldehyde 
• 76238-97-6 C₁₀H₁₂O₃ 
• 1271727-99-1 C₂₈H₃₁NO₄ 
• 1391114-17-2 C₂₅H₂₈O₄ 
• 1268719-17-0 2-benzyloxy-4-methoxy-5-ethylbenzaldehyde 
• 2896-60-8 4-ethyl-1,3-benzenediol 
• 853917-06-3 5-(2-benzyloxy-5-ethyl-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole 

Relevant articles and documents

Convenient synthesis of an isoxazole compound, KRIBB3, as an anticancer agent

A diaryl isoxazole compound, KRIBB3, which exhibits strong antimigratory and antimitotic activities against cancer cells, was prepared in a practical synthetic way. The synthetic method may provide easy access to KRIBB3 analogs with various substituents a

NEW DIARYL-ISOXAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME FOR THE PREVENTION AND THE TREATMENT OF CANCERS

The present invention relates to new diaryl-isoxazole derivatives, and pharmaceutical compositions containing the same as an effective ingredient for the prevention and the treatment of cancers. Diaryl-isoxazole derivatives of the present invention inhibi

Pharmaceutical compositions of diaryl-isoxazole derivatives for the prevention and treatment of cancers

The present invention relates to a pharmaceutical composition for the prevention and the treatment of cancers containing diaryl-isoxazole derivatives as an effective ingredient. Diaryl-isoxazole derivatives of the present invention inhibit metastasis of b