129415-27-6 Usage
General Description
1,2,6,7-tetrahydroxypyrrolizidine is a toxic alkaloid found in various plant species, including those in the genera Senecio, Crotalaria, and Heliotropium. The compound is known for its hepatotoxic and carcinogenic properties, and ingestion or exposure to this chemical can cause liver damage and even lead to the development of liver cancer. 1,2,6,7-tetrahydroxypyrrolizidine is not only present in various plants but it can also be found in honey, where bees have collected nectar from plants containing the alkaloid. Due to its harmful effects on human health, the presence of 1,2,6,7-tetrahydroxypyrrolizidine in food and herbal products is of concern, and efforts are being made to monitor and limit exposure to this toxic compound.
Check Digit Verification of cas no
The CAS Registry Mumber 129415-27-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,4,1 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 129415-27:
(8*1)+(7*2)+(6*9)+(5*4)+(4*1)+(3*5)+(2*2)+(1*7)=126
126 % 10 = 6
So 129415-27-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H13NO4/c9-3-1-8-2-4(10)7(12)5(8)6(3)11/h3-7,9-12H,1-2H2/t3-,4+,5?,6-,7+
129415-27-6Relevant articles and documents
Effect on human liver glycosidases and short syntheses of 1 alpha,2 alpha,6 alpha,7 alpha,7a beta-1,2,6,7-tetrahydroxypyrrolizidine from D-glycero-D-gulo-heptono-1,4-lactone.
Collin,Fleet,Haraldsson,Cenci di Bello,Winchester
, p. 105 - 116 (2007/10/02)
The synthesis of 1 alpha,2 alpha,6 alpha,7 alpha,7a beta-1,2,6,7-tetrahydroxypyrrolizidine (1) from D-glycero-D-gulo-heptono-1,4-lactone (6) by two different routes is reported. The effects of 1 on the inhibition of 15 human liver glycosidases are describ
